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Chemical structure of <t>polyhexamethylene</t> <t>biguanide</t> hydrochloride <t>(PHMB).</t>
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Biosynth Carbosynth polyhexanide (phmb
The effectiveness of the tested antimicrobials against K. pneumoniae biofilm formed on the surface of polystyrene in an artificial urine medium with glucose (AUMg). Minimal biofilm eradication concentration (MBEC) values are expressed in mg/L; the % values represent the survival rate at 256 mg/L; X indicates no effect of the maximum tested concentration.
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Chemical structure of polyhexamethylene biguanide hydrochloride (PHMB).

Journal: Polymers

Article Title: Surface-Modified Carboxylated Cellulose Nanofiber Hydrogels for Prolonged Release of Polyhexamethylene Biguanide Hydrochloride (PHMB) for Antimicrobial Applications

doi: 10.3390/polym15173572

Figure Lengend Snippet: Chemical structure of polyhexamethylene biguanide hydrochloride (PHMB).

Article Snippet: Polyhexamethylene biguanide (PHMB) was purchased from Carbosynth Ltd., Compton, UK.

Techniques:

The effectiveness of the tested antimicrobials against K. pneumoniae biofilm formed on the surface of polystyrene in an artificial urine medium with glucose (AUMg). Minimal biofilm eradication concentration (MBEC) values are expressed in mg/L; the % values represent the survival rate at 256 mg/L; X indicates no effect of the maximum tested concentration.

Journal: Pathogens

Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters

doi: 10.3390/pathogens11010042

Figure Lengend Snippet: The effectiveness of the tested antimicrobials against K. pneumoniae biofilm formed on the surface of polystyrene in an artificial urine medium with glucose (AUMg). Minimal biofilm eradication concentration (MBEC) values are expressed in mg/L; the % values represent the survival rate at 256 mg/L; X indicates no effect of the maximum tested concentration.

Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

Techniques: Concentration Assay

Comparison of the effectiveness of selected compounds in the eradication of K. pneumoniae clinical strain K81 biofilm from the catheter surface under flow conditions. C+, control of growth; H 2 O, sterile water; PHMB, polyhexanide; OCT, octenidine; BET, betaine; SAP, saponin; P-ETOH, phenoxyethanol. Statistically significant differences are marked with asterisks.

Journal: Pathogens

Article Title: The In Vitro Ability of Klebsiella pneumoniae to Form Biofilm and the Potential of Various Compounds to Eradicate It from Urinary Catheters

doi: 10.3390/pathogens11010042

Figure Lengend Snippet: Comparison of the effectiveness of selected compounds in the eradication of K. pneumoniae clinical strain K81 biofilm from the catheter surface under flow conditions. C+, control of growth; H 2 O, sterile water; PHMB, polyhexanide; OCT, octenidine; BET, betaine; SAP, saponin; P-ETOH, phenoxyethanol. Statistically significant differences are marked with asterisks.

Article Snippet: The efficacy of 0.05% solutions of polyhexanide (PHMB) (Carbosynth, Ltd., Compton, Newbery, UK) and octenidine (OCT) (Dishman Pharmaceuticals & Chemicals Ltd., Ahmedabad, India) and 0.1% solutions of betaine (BET) (Merck, Darmstadt, Germany), saponin (SAP) (Merck, Darmstadt, Germany) and phenoxyethanol (P-ETOH) (Merck, Darmstadt, Germany) was tested.

Techniques: Comparison, Control, Sterility